Description

Methyl 2-O,3-o-Dimethyl-α-D-Glucopyranosiduronic Acid Methyl Ester is a key protected derivative of glucuronic acid, serving as a critical chiral building block and synthetic intermediate. Its value lies in providing a chemically defined, stable scaffold for the controlled synthesis of complex carbohydrates, glycoconjugates, and other bioactive molecules. This compound is essential for researchers and manufacturers in pharmaceutical development, advanced carbohydrate chemistry, and the production of specialized fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of glycosylated drugs, prodrugs, and targeted therapeutics.
• Carbohydrate Chemistry Research: Used as a protected starting material for the controlled assembly of oligosaccharides and complex glycans.
• Glycoconjugate Synthesis: A key building block for creating glycopeptides, glycolipids, and other biologically active conjugates.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring specific sugar-derived chiral centers.
• Biochemical Tool Development: Utilized in the design and synthesis of enzyme inhibitors, receptor ligands, and diagnostic probes.
• Standards and Reference Materials: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Methyl 2-O,3-o-Dimethyl-α-D-Glucopyranosiduronic Acid Methyl Ester
CAS No.	51433-21-7
Molecular Formula	C11H18O8
Molecular Weight	278.26 g/mol
Synonyms	Methyl (methyl 2,3-di-O-methyl-α-D-glucopyranosid)uronate; Methyl 2,3-Di-O-methyl-α-D-glucopyranosiduronic Acid Methyl Ester; α-D-Glucopyranosiduronic acid, methyl, methyl ester, 2,3-di-O-methyl-; Methyl 2,3-di-O-methyl-α-D-glucuronate methyl glycoside; 2,3-Di-O-methyl-α-D-methyl glucuronate; Protected Methyl Glucuronate; Methyl α-D-Glucopyranosiduronic Acid Methyl Ester, 2,3-Di-O-methyl Derivative
EINECS	Contact for details

Quality Control

Our Methyl 2-O,3-o-Dimethyl-α-D-Glucopyranosiduronic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and optical rotation measurement, to ensure identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Optical Rotation [α]²⁰D	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.