Description

(3-Trifluoromethyl-Benzyl)-Hydrazine is a specialized aromatic hydrazine derivative featuring a benzyl group substituted with a trifluoromethyl moiety. This compound matters as a versatile and high-value building block in advanced organic synthesis, where its unique structure enables the introduction of both hydrazine and fluorinated aromatic functionalities. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients, particularly in medicinal chemistry for lead optimization and scaffold diversification.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of heterocyclic compounds, such as pyrazoles and indazoles, for drug discovery programs targeting CNS disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic materials with tailored surface properties.
• Chemical Biology Probes: Utilized to create hydrazone-based linkers and fluorinated tags for labeling and studying biomolecules.

Basic Information

Product Name	(3-Trifluoromethyl-Benzyl)-Hydrazine
CAS No.	51421-34-2
Molecular Formula	C8H9F3N2
Molecular Weight	190.17 g/mol
Synonyms	1-[(3-Trifluoromethyl)phenyl]methylhydrazine; 1-(3-Trifluoromethylbenzyl)hydrazine; m-Trifluoromethylbenzylhydrazine; (3-(Trifluoromethyl)benzyl)hydrazine; α-Hydrazino-α-(trifluoromethyl)toluene; 3-Trifluoromethylbenzyl Hydrazine; (m-Trifluoromethylbenzyl)hydrazine; Hydrazine, [(3-(trifluoromethyl)phenyl)methyl]-
EINECS	Contact for details

Quality Control

Our (3-Trifluoromethyl-Benzyl)-Hydrazine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot undergoes rigorous analytical testing, including HPLC for assay and purity, and NMR for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.