Description

1,8-Diazabicyclo[5.4.0]undec-7-ene, compound with p-toluenesulfonic acid (1:1) is a high-purity, non-nucleophilic organic base salt, widely recognized for its superior performance in demanding synthetic applications. This compound matters because it combines the potent basicity and low nucleophilicity of DBU with the handling and stability advantages of a crystalline tosylate salt, offering a reliable and efficient reagent for critical chemical transformations. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise control over base-catalyzed reactions, including eliminations, isomerizations, and condensations.

Application

• Pharmaceutical Synthesis: As a powerful, non-nucleophilic base for deprotonation, elimination (e.g., Hofmann-type), and isomerization reactions in API (Active Pharmaceutical Ingredient) manufacturing.
• Polymer Chemistry: Catalyst and co-catalyst in the production of polyurethanes, polycarbonates, and other specialty polymers, where it facilitates controlled polymerization.
• Agrochemical Production: Key reagent in the synthesis of complex pesticide and herbicide molecules, enabling high-yield condensation and cyclization steps.
• Fine Chemical Manufacturing: Employed in the synthesis of dyes, pigments, and photographic chemicals due to its efficiency in base-mediated coupling reactions.
• Academic & R&D Laboratories: A staple reagent for methodological development in organic synthesis, particularly for reactions sensitive to nucleophilic interference.
• Electrolyte Additive: Potential use as a stabilizing agent or proton scavenger in advanced battery electrolyte formulations.

Basic Information

Item	Details
Product Name	1,8-Diazabicyclo[5.4.0]undec-7-ene, compound with p-toluenesulfonic acid (1:1)
CAS No.	51376-18-2
Molecular Formula	C₁₁H₁₈N₂·C₇H₈O₃S
Molecular Weight	406.52 g/mol
Synonyms	DBU Tosylate; DBU p-Toluenesulfonate; 1,8-Diazabicyclo[5.4.0]undec-7-enium 4-methylbenzenesulfonate; DBU TsOH; DBU Tosylate Salt; 2,3,4,6,7,8,9,10-Octahydropyrimido[1,2-a]azepin-1-ium 4-methylbenzenesulfonate; DBU monotosylate
EINECS	Contact for details

Quality Control

Our 1,8-Diazabicyclo[5.4.0]undec-7-ene tosylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.