Description

2-Chloro-1-(3,4-Difluorophenyl)Ethanol is a versatile chiral building block and key pharmaceutical intermediate of significant commercial importance. Its value lies in its functionalized aromatic structure, which is critical for synthesizing complex molecules in modern drug discovery and development. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the production of active ingredients.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) agents and other therapeutic compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the difluorophenyl moiety for enhanced biological activity.
• Liquid Crystal Material Precursor: Serves as a starting material in the synthesis of fluorinated liquid crystals for display technologies.
• Organic Synthesis Building Block: Employed in asymmetric synthesis and cross-coupling reactions to construct more complex molecular architectures in fine chemical production.
• Chemical Research & Development: Utilized in academic and industrial R&D labs for method development and exploring new chemical entities.

Basic Information

Product Name	2-Chloro-1-(3,4-Difluorophenyl)Ethanol
CAS No.	51336-97-1
Molecular Formula	C8H7ClF2O
Molecular Weight	192.59 g/mol
Synonyms	2-Chloro-1-(3,4-difluorophenyl)ethan-1-ol; 1-(3,4-Difluorophenyl)-2-chloroethanol; α-Chloro-3,4-difluorobenzeneethanol; 2-Chloro-1-(3,4-difluorophenyl)ethyl alcohol; 3,4-Difluoro-α-(chloromethyl)benzyl alcohol; (RS)-2-Chloro-1-(3,4-difluorophenyl)ethanol; 51336-97-1
EINECS	Contact for details

Quality Control

Our 2-Chloro-1-(3,4-Difluorophenyl)Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.