Description

Methyl-2-Deoxy-β-D-Ribofuranoside CAS NO 51255-18-6 is a specialized carbohydrate derivative and a key protected intermediate in nucleoside and oligonucleotide synthesis. Its primary value lies in providing a versatile, chemically stable scaffold for constructing modified nucleic acid analogs and other bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and agrochemical industries focused on developing novel therapeutics, diagnostic probes, and research tools.

Application

• Nucleoside & Nucleotide Synthesis: A crucial building block for the chemical synthesis of modified nucleosides and their corresponding phosphoramidites for solid-phase oligonucleotide assembly.
• Antiviral & Anticancer Drug Development: Serves as a key intermediate in the research and production of nucleoside analog prodrugs targeting viral polymerases and cellular replication pathways.
• Oligonucleotide Therapeutics: Used in the preparation of antisense oligonucleotides (ASOs), small interfering RNA (siRNA), and aptamers for gene silencing and targeted therapy applications.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies and for probing carbohydrate-active enzymes and metabolic pathways.
• Glycochemistry & Glycobiology: Acts as a protected glycosyl donor or acceptor for the synthesis of complex carbohydrates, glycoconjugates, and glycomimetics.
• Agrochemical Research: Utilized in the development of novel nucleoside-based pesticides and plant growth regulators.

Basic Information

Product Name	Methyl-2-Deoxy-β-D-Ribofuranoside
CAS No.	51255-18-6
Molecular Formula	C6H12O4
Molecular Weight	148.16 g/mol
Synonyms	Methyl 2-Deoxy-β-D-ribofuranoside; 2-Deoxy-β-D-ribofuranose Methyl Glycoside; Methyl 2-Deoxy-β-D-erythro-pentofuranoside; 1-O-Methyl-2-deoxy-β-D-ribofuranose; β-Methyl 2-Deoxyribofuranoside; 2-Deoxy-β-D-ribofuranoside Methyl Ester; 2-Deoxy-β-D-ribofuranosyl Methyl Ether; Methyl β-D-2-Deoxyribofuranoside
EINECS	Contact for details

Quality Control

Our Methyl-2-Deoxy-β-D-Ribofuranoside is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research and synthesis. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which can affect stability and performance in sensitive synthetic applications.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.