Description

(S)-2-Isopropylpyrrolidine Hydrochloride is a high-purity chiral building block and intermediate of significant importance in modern synthetic chemistry. Its value lies in its well-defined stereochemistry, which is critical for imparting specific biological activity in final target molecules. This compound is primarily needed by pharmaceutical R&D and process chemistry teams for the development of new active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise stereocontrol.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, especially those targeting the central nervous system (CNS).
• Asymmetric Catalysis: Used as a precursor or ligand in the development of chiral catalysts for enantioselective synthesis.
• Agrochemical Research: Serves as a building block for novel, stereochemically-defined pesticides and herbicides.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and enzyme inhibitors.
• Academic & Process Research: Utilized in methodological development and scale-up studies for chiral amine synthesis.

Basic Information

Product Name	(S)-2-Isopropylpyrrolidine Hydrochloride
CAS No.	51207-71-7
Molecular Formula	C7H16ClN
Molecular Weight	149.66 g/mol
Synonyms	(S)-2-Isopropylpyrrolidine HCl; (S)-2-(1-Methylethyl)pyrrolidine hydrochloride; (S)-(-)-2-Isopropylpyrrolidine hydrochloride; L-2-Isopropylpyrrolidine hydrochloride; (S)-2-Isopropylpyrrolidinium chloride; Pyrrolidine, 2-(1-methylethyl)-, hydrochloride, (2S)-; (S)-2-(Propan-2-yl)pyrrolidine hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-2-Isopropylpyrrolidine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Production adheres to cGMP guidelines where applicable, and all materials are supported by comprehensive analytical documentation. Certificates of Analysis (COA) detailing identity, purity (HPLC/Chiral HPLC), and impurity profiles are provided with each shipment to guarantee compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.