Description

1-Bromo-1-Nitrocyclobutane is a versatile halogenated nitroalkane building block of significant interest in advanced organic synthesis. Its unique structure, featuring both bromine and nitro functional groups on a strained cyclobutane ring, makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for introducing functionalized cyclobutane motifs.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where the nitrocyclobutane scaffold imparts specific biological activity.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers and advanced materials with tailored properties.
• Organic Synthesis Building Block: Employed in various name reactions and cascade processes for the construction of complex, strained-ring systems and natural product analogs.
• Chemical Biology Probes: Useful for synthesizing labeled compounds or probes for studying biological mechanisms and interactions.

Basic Information

Product Name	1-Bromo-1-Nitrocyclobutane
CAS No.	51175-81-6
Molecular Formula	C4H6BrNO2
Molecular Weight	180.00 g/mol
Synonyms	1-Bromo-1-nitrocyclobutane; 1-Nitro-1-bromocyclobutane; Bromonitrocyclobutane; Cyclobutane, 1-bromo-1-nitro-; NSC 163083
EINECS	Contact for details

Quality Control

Our 1-Bromo-1-Nitrocyclobutane is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and spectroscopic identification, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming batch-specific identity, purity, and quality parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, open flames, and incompatible materials. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.