Description

2-Fluoro-2-Deoxy-D-Galactopyranose is a fluorinated carbohydrate derivative, a key building block in synthetic organic chemistry and glycobiology research. Its primary value lies in its role as a stable glycosyl donor or acceptor for the synthesis of complex oligosaccharides and glycoconjugates, where the fluorine atom acts as a versatile handle for further chemical manipulation. This compound is essential for researchers and manufacturers in the pharmaceutical, diagnostic, and biotechnology sectors, particularly for developing novel glycomimetics, enzyme inhibitors, and radiolabeled probes for medical imaging.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of novel fluorinated drugs, enzyme inhibitors, and glycomimetics targeting metabolic disorders and cancers.
• Glycobiology Research: Used as a stable, non-hydrolyzable analog of galactose to study carbohydrate-protein interactions, enzyme mechanisms, and cell signaling pathways.
• Diagnostic Probe Development: Serves as a backbone for creating radiolabeled (e.g., 18F) tracers for Positron Emission Tomography (PET) imaging.
• Carbohydrate Chemistry: A versatile building block for the chemo-enzymatic synthesis of complex oligosaccharides, glycopeptides, and glycolipids.
• Bioconjugation: Enables the site-specific fluorination of biomolecules for stability studies, metabolic labeling, and creating biophysical probes.

Basic Information

Product Name	2-Fluoro-2-Deoxy-D-Galactopyranose
CAS No.	51146-53-3
Molecular Formula	C6H11FO5
Molecular Weight	182.15 g/mol
Synonyms	2-Deoxy-2-fluoro-D-galactose; 2-Fluoro-D-galactose; 2-FDG; 2-F-2-Deoxy-D-galactose; D-Galactose, 2-deoxy-2-fluoro-; 2-Fluorogalactose; (2R,3R,4S,5R)-2-Fluoromethyltetrahydro-2H-pyran-3,4,5-triol
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-2-Deoxy-D-Galactopyranose is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, which include data from HPLC, NMR, and specific rotation tests. Our quality commitment aligns with the standards required for research and cGMP manufacturing applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	[α]D20: +50° to +60° (c=1 in H2O)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.