Description

(αr,4S,9Aβ)-Octahydro-6α-Methyl-α-Propyl-2H-Quinolizine-4-Ethanol Benzoate CAS NO 51105-10-3 is a high-purity, stereochemically defined quinolizidine derivative. This compound is valued for its role as a critical advanced pharmaceutical intermediate in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of specialized therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of complex alkaloid-based drug candidates.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new pharmacophores.
• Process Chemistry: Serves as a critical intermediate in scale-up and optimization of API manufacturing routes.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Chemical Synthesis: Utilized in organic synthesis for constructing complex polycyclic nitrogen-containing structures.

Basic Information

Product Name	(αr,4S,9Aβ)-Octahydro-6α-Methyl-α-Propyl-2H-Quinolizine-4-Ethanol Benzoate
CAS No.	51105-10-3
Molecular Formula	C22H33NO2
Molecular Weight	343.51 g/mol
Synonyms	Benzoic acid, 2-[(1S,4R,6R,7R,9S)-7-methyl-1-propyl-2,5-diazatricyclo[7.3.1.04,9]tridecan-6-yl]ethyl ester; (1S,4R,6R,7R,9S)-6-[2-(Benzoyloxy)ethyl]-7-methyl-1-propyl-2,5-diazatricyclo[7.3.1.04,9]tridecane; 4-Ethanol Benzoate derivative of Octahydro-6α-Methyl-α-Propyl-2H-Quinolizine; Quinolizidine-4-ethanol benzoate derivative
EINECS	Contact for details

Quality Control

Our (αr,4S,9Aβ)-Octahydro-6α-Methyl-α-Propyl-2H-Quinolizine-4-Ethanol Benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring compliance with stringent pharmaceutical-grade requirements. Comprehensive Certificates of Analysis (COA) with full traceability are provided.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.