Description

1,2,3,4-Tetrahydro-4-Methyl-1,2-Naphthalenediol is a specialized dihydroxylated tetralin derivative, a key chiral building block in advanced organic synthesis. Its unique fused-ring structure with vicinal hydroxyl groups makes it a valuable precursor for synthesizing complex molecules with high stereochemical control. This compound is essential for R&D and production in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and chiral ligands.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of complex drug molecules, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Catalyst Ligand Precursor: Used to develop novel chiral ligands for asymmetric hydrogenation and other enantioselective catalytic reactions.
• Fine Chemical Synthesis: Serves as a building block for fragrances, agrochemicals, and other high-value specialty chemicals requiring specific stereochemistry.
• Academic & Industrial Research: Employed in methodological studies for new synthetic routes and the exploration of structure-activity relationships (SAR).
• Material Science Intermediate: Potential use in the synthesis of advanced polymers and liquid crystals with specific optical properties.

Basic Information

Product Name	1,2,3,4-Tetrahydro-4-Methyl-1,2-Naphthalenediol
CAS No.	51086-38-5
Molecular Formula	C11H14O2
Molecular Weight	178.23 g/mol
Synonyms	4-Methyl-1,2,3,4-tetrahydronaphthalene-1,2-diol; cis-4-Methyl-1,2,3,4-tetrahydronaphthalene-1,2-diol; 1,2-Dihydroxy-4-methyl-1,2,3,4-tetrahydronaphthalene; 4-Methyl-1,2-dihydroxytetralin; (±)-4-Methyl-1,2,3,4-tetrahydronaphthalene-1,2-diol; 1,2,3,4-Tetrahydro-4-methyl-1,2-naphthalenediol (racemic); Tetralin-1,2-diol derivative
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydro-4-Methyl-1,2-Naphthalenediol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.