Description

(4-Fluorobenzyl)Triphenylphosphonium Bromide is a high-purity, organophosphorus salt widely utilized as a key reagent in advanced organic synthesis. Its primary value lies in its role as a stable Wittig reagent, enabling the efficient formation of carbon-carbon double bonds to introduce fluorinated benzyl groups into target molecules. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where it facilitates the development of novel fluorinated compounds with tailored properties.

Application

• Wittig Olefination Reactions: As a crucial ylide precursor for the synthesis of fluorinated alkenes and styrene derivatives.
• Pharmaceutical Intermediate Synthesis: For constructing fluorinated scaffolds in active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Development: In the production of fluorinated pesticides, herbicides, and plant growth regulators.
• Liquid Crystal & OLED Material Research: As a building block for fluorinated organic electronic materials.
• Specialty Polymer Modification: To incorporate fluorobenzyl side chains, altering polymer properties like solubility and thermal stability.
• Cross-Coupling Reaction Catalyst/Precursor: In palladium-catalyzed reactions for forming carbon-carbon bonds.
• Academic & Process R&D: A versatile tool for methodological development and scale-up chemistry in laboratory and pilot plant settings.

Basic Information

Product Name	(4-Fluorobenzyl)Triphenylphosphonium Bromide
CAS No.	51044-11-2
Molecular Formula	C25H21BrFP+ • Br-
Molecular Weight	483.31 g/mol (as bromide salt)
Synonyms	4-Fluorobenzyltriphenylphosphonium Bromide; (p-Fluorobenzyl)triphenylphosphonium Bromide; [(4-Fluorophenyl)methyl]triphenylphosphonium Bromide; (4-Fluorobenzyl)triphenyl-λ5-phosphanebromide; Triphenyl(4-fluorobenzyl)phosphonium Bromide; Phosphonium, (4-fluorobenzyl)triphenyl-, bromide (1:1); F-BnTPP Br
EINECS	Contact for details

Quality Control

Our (4-Fluorobenzyl)Triphenylphosphonium Bromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and elemental analysis, to ensure high chemical purity and consistent performance. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.