Description

n-Acetyl-β-Neuraminic Acid Methyl Ester Monohydrate is a key derivative of sialic acid, a critical carbohydrate moiety in glycobiology. This high-purity intermediate is essential for the synthesis and research of complex glycoconjugates, enabling precise study of cell surface interactions and signaling. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors for developing novel therapeutics, vaccines, and analytical reagents.

Application

• Glycoconjugate Synthesis: A vital building block for the chemical and enzymatic synthesis of sialylated oligosaccharides, glycopeptides, and glycolipids.
• Pharmaceutical Research: Used in the development of sialidase inhibitors, anti-influenza drugs, and other therapeutics targeting sialic acid-mediated biological pathways.
• Diagnostic Reagent Production: Serves as a precursor for labeling compounds and calibrants used in assays for detecting sialic acid levels or specific glycosylation patterns.
• Biochemical Research: Employed as a standard or substrate in enzymatic studies of sialyltransferases, neuraminidases, and other glycosyl-related enzymes.
• Vaccine Development: Utilized in the research and production of conjugate vaccines where specific carbohydrate antigens are critical.
• Cell Biology Studies: Applied to investigate the role of sialic acids in cell adhesion, immune response modulation, and pathogen recognition.

Basic Information

Item	Details
Product Name	n-Acetyl-β-Neuraminic Acid Methyl Ester Monohydrate
CAS No.	50998-13-5
Molecular Formula	C13H23NO10 • H2O
Molecular Weight	359.33 g/mol (Monohydrate)
Synonyms	5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-non-2-ulopyranosonic Acid Methyl Ester Monohydrate; Methyl 5-acetamido-3,5-dideoxy-D-glycero-α-D-galacto-non-2-ulopyranosidonate Monohydrate; Methyl N-Acetylneuraminate Monohydrate; Methyl NANA; Neu5Ac Methyl Ester Monohydrate; Sialic Acid Methyl Ester Monohydrate; N-Acetylneuraminic Acid Methyl Ester Monohydrate
EINECS	Contact for details

Quality Control

Our n-Acetyl-β-Neuraminic Acid Methyl Ester Monohydrate is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, IR), to ensure it meets the exacting standards required for research and synthesis. Certificates of Analysis (COA) detailing all specifications are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to ambient conditions should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	4.0% - 6.0%
Specific Rotation	Contact for details
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.