Description

2-o-Methyl-α-D-n-Acetylneuraminic Acid is a chemically modified derivative of N-acetylneuraminic acid, a fundamental sialic acid. This compound is a critical building block and reference standard in advanced biochemical research and pharmaceutical development. It is primarily utilized by research institutions and manufacturers in the life sciences sector for studying carbohydrate-protein interactions, developing diagnostic tools, and synthesizing novel glycoconjugates.

Application

• Biochemical Research: As a key intermediate and reference standard for studying sialic acid metabolism, enzyme kinetics (sialyltransferases, neuraminidases), and glycan biosynthesis pathways.
• Pharmaceutical Development: Serves as a precursor in the synthesis of more complex sialic acid analogs and glycomimetics for potential therapeutic applications, including antiviral and anti-inflammatory agents.
• Diagnostic Reagent Synthesis: Used in the development of diagnostic assays and probes that target sialic acid-binding proteins, such as selectins and siglecs, relevant to inflammation and cancer biology.
• Glycoconjugate Chemistry: A vital starting material for the chemical and enzymatic synthesis of defined oligosaccharides, glycopeptides, and glycolipids for structural and functional studies.
• Academic & Industrial R&D: Employed in laboratories focused on glycoscience, immunology, and microbiology to investigate host-pathogen interactions and cell surface recognition events.

Basic Information

Product Name	2-o-Methyl-α-D-n-Acetylneuraminic Acid
CAS No.	50930-22-8
Molecular Formula	C12H21NO9
Molecular Weight	323.30 g/mol
Synonyms	2-O-Methyl-N-acetylneuraminic acid; 2-O-Methyl-Neu5Ac; 2-O-Methyl-5-acetamido-3,5-dideoxy-D-glycero-D-galacto-non-2-ulopyranosonic acid; Methylated Sialic Acid; 2-OMe Neu5Ac; 2-O-Methyl-α-D-N-acetylneuraminic acid; N-Acetyl-2-O-methylneuraminic acid
EINECS	Contact for details

Quality Control

Every batch of 2-o-Methyl-α-D-n-Acetylneuraminic Acid is produced and tested under stringent quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.