Description

1-Bromo-8-(Tetrahydropyranyloxy)Octane is a specialized bifunctional organic intermediate featuring both a bromoalkyl chain and a tetrahydropyranyl (THP) protected hydroxyl group. This unique structure makes it a valuable building block for the controlled synthesis of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily utilized by R&D chemists and process development scientists in the life sciences and advanced materials sectors for constructing molecular scaffolds with precise chain length and protected functionality.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring specific alkyl chain linkers.
• Ligand and Catalyst Synthesis: Used to prepare specialized ligands and phase-transfer catalysts with tailored hydrophobicity and chain length.
• Polymer Chemistry: Serves as a functional monomer or chain transfer agent in the production of specialty polymers with pendant reactive groups.
• Material Science: Employed in the surface modification of materials and the creation of self-assembled monolayers (SAMs).
• Organic Synthesis: Versatile reagent for nucleophilic substitution reactions (via the bromo group) and subsequent deprotection of the THP ether to reveal a primary alcohol.
• Life Sciences Research: Useful in probe and linker molecule synthesis for bioconjugation and diagnostic applications.

Basic Information

Product Name	1-Bromo-8-(Tetrahydropyranyloxy)Octane
CAS No.	50816-20-1
Molecular Formula	C₁₃H₂₅BrO₂
Molecular Weight	293.24 g/mol
Synonyms	8-(Tetrahydro-2H-pyran-2-yloxy)-1-bromooctane; 1-Bromo-8-((tetrahydro-2H-pyran-2-yl)oxy)octane; Octane, 1-bromo-8-(tetrahydro-2H-pyran-2-yloxy)-; THP-protected 8-bromooctanol; 8-Bromooctyl tetrahydropyranyl ether; 2-((8-Bromooctyl)oxy)tetrahydro-2H-pyran
EINECS	Contact for details

Quality Control

Our 1-Bromo-8-(Tetrahydropyranyloxy)Octane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be handled accordingly.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.