Description

Indium Trichloride-In111 is a high-purity, isotopically labeled inorganic salt, specifically the chloride salt of Indium-111. This compound is critical for applications requiring precise radiolabeling and traceability in advanced diagnostic and research fields. It is primarily utilized by radiopharmaceutical manufacturers, nuclear medicine research facilities, and specialized chemical synthesis laboratories for developing targeted imaging agents.

Application

• Radiopharmaceutical Precursor: Serves as the primary starting material for synthesizing Indium-111 (111In) labeled diagnostic agents, such as 111In-pentetreotide (OctreoScan) and 111In-capromab pendetide (ProstaScint).
• Nuclear Medicine Research: Used in preclinical and clinical research for developing novel radiolabeled peptides, antibodies, and nanoparticles for SPECT (Single-Photon Emission Computed Tomography) imaging.
• Radiolabeling of Biomolecules: Essential for chelating 111In to DOTA, DTPA, and other bifunctional chelators attached to targeting vectors like antibodies and peptides.
• Quality Control & Reference Standard: Acts as a critical reference standard in QC laboratories to validate the purity and specific activity of final radiopharmaceutical products.
• Chemical Synthesis: Employed in specialized inorganic and organometallic synthesis where an isotopically labeled indium source is required.

Basic Information

Product Name	Indium Trichloride-In111
CAS No.	50800-85-6
Molecular Formula	111InCl3
Molecular Weight	Approx. 264.18 g/mol (for 111In isotope)
Synonyms	Indium-111 Chloride; 111InCl3; Indium (111In) Chloride; Indium Trichloride, isotope of mass 111; Indium(III) Chloride-111; Carrier-Free Indium-111 Chloride; Radionuclide Generator Eluate (from 111Cd).
EINECS	Contact for details

Quality Control

Every batch of Indium Trichloride-In111 is manufactured and tested under strict cGMP guidelines to ensure the highest standards of radiochemical purity, radionuclidic purity, and specific activity required for human use. Our quality system includes rigorous testing for identity, purity, sterility (where applicable), and apyrogenicity. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results for all release specifications, including compliance with relevant pharmacopoeial monographs (e.g., USP, Ph. Eur.).

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. Handle and store in accordance with all applicable radiation safety regulations and guidelines.

Specification

Item	Specification
Appearance	Clear, colorless solution
Identification (Gamma Spectroscopy)	Gamma spectrum corresponds to Indium-111
Radionuclidic Purity	≥ 99.9%
Radiochemical Purity (HPLC/TLC)	≥ 95.0%
Specific Activity	Contact for details
pH	1.0 - 3.0
Cd-109 Content	< 0.1%
Sterility Test (if supplied sterile)	Sterile
Bacterial Endotoxins (LAL)	< 17.5 EU/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.