Description

2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid hydrazide is a high-purity, specialized organic compound featuring a benzoic acid hydrazide core substituted with trifluoroethoxy groups. This unique structure makes it a valuable advanced intermediate for the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients. The compound, identified by CAS No. 50778-75-1, is essential for projects requiring precise fluorinated building blocks.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in developing new-generation herbicides, fungicides, or insecticides where the trifluoroethoxy groups can influence potency and environmental fate.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis or metal-organic frameworks (MOFs).
• Material Science: Potential monomer or additive for synthesizing high-performance polymers with specific thermal or chemical resistance properties.
• Chemical Biology Probes: Utilized in the design of activity-based probes or fluorescent tags for studying biological processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid hydrazide
CAS No.	50778-75-1
Molecular Formula	C11H9F6N2O3
Molecular Weight	322.19 g/mol
Synonyms	Benzoic acid, 2,5-bis(2,2,2-trifluoroethoxy)-, hydrazide; 2,5-Bis(2,2,2-trifluoroethoxy)benzohydrazide; [2,5-Bis(2,2,2-trifluoroethoxy)phenyl]formic acid hydrazide; Hydrazide of 2,5-bis(2,2,2-trifluoroethoxy)benzoic acid; 50778-75-1; 2,5-Di(2,2,2-trifluoroethoxy)benzoic acid hydrazide
EINECS	Contact for details

Quality Control

Every batch of 2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid hydrazide is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements of research and development applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment. Our quality protocols are designed to support cGMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for long-term storage. Keep away from strong oxidizers and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC, Area %)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.