Description

Methyl-2,3:4,6-Di-o-Isopropylidene-D-Mannopyranoside is a key protected carbohydrate derivative, specifically a mannose acetonide, widely used as a versatile chiral building block and synthetic intermediate. Its primary value lies in its ability to provide a rigid, protected scaffold for the stereoselective synthesis of complex molecules, ensuring high chemical and optical purity in downstream products. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs), nucleoside analogs, and specialty glycosides.

Application

• Pharmaceutical Intermediate: A crucial chiral precursor for the synthesis of antiviral and anticancer nucleoside drugs.
• Glycochemistry & Glycobiology: Serves as a protected mannose donor for the construction of complex oligosaccharides, glycoconjugates, and glycomimetics.
• Asymmetric Synthesis: Used as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Agrochemical Development: Employed in the research and production of chiral active ingredients for advanced crop protection agents.
• Fine Chemical Synthesis: A building block for flavors, fragrances, and other high-value specialty chemicals requiring specific stereochemistry.
• Academic & Industrial R&D: A standard reagent in carbohydrate chemistry research for method development and exploring new synthetic pathways.

Basic Information

Product Name	Methyl-2,3:4,6-Di-o-Isopropylidene-D-Mannopyranoside
CAS No.	50705-56-1
Molecular Formula	C13H22O6
Molecular Weight	274.31 g/mol
Synonyms	Methyl 2,3:4,6-Di-O-isopropylidene-α-D-mannopyranoside; Methyl α-D-Mannopyranoside Diacetonide; 1,2:5,6-Di-O-isopropylidene-α-D-mannofuranose Methyl Glycoside; D-Mannose Diacetonide Methyl Glycoside; Methyl Di-O-isopropylidene-α-D-mannopyranoside; α-Methyl Di-O-isopropylidene-D-mannoside; 50705-56-1; Mannose Acetonide Methyl Glycoside
EINECS	Contact for details

Quality Control

Our Methyl-2,3:4,6-Di-o-Isopropylidene-D-Mannopyranoside is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets the highest standards of chemical purity and stereochemical integrity. Certificates of Analysis (COA) detailing identity, purity (HPLC/GC), optical rotation, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]²⁰D	-18° to -22° (c=1 in CHCl₃)
Melting Point	154°C - 158°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.