Description

2-Chloro-1-(2,3,5,6-Tetramethylphenyl)Ethanone is a specialized aromatic ketone derivative, recognized for its role as a versatile synthetic intermediate in advanced organic chemistry. Its value lies in the unique steric and electronic properties imparted by the tetramethylphenyl (durene) group, which is critical for directing regioselective reactions and constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical sectors, where it is used to synthesize novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in creating sterically hindered aromatic systems.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its structural motif for bioactivity.
• Material Science Research: Serves as a precursor for organic ligands and functional monomers in polymer and coordination chemistry.
• Chemical Research & Development: A valuable reagent for method development in organic synthesis, including Friedel-Crafts acylation and cross-coupling reactions.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals and complex organic molecules for various industrial applications.

Basic Information

Product Name	2-Chloro-1-(2,3,5,6-Tetramethylphenyl)Ethanone
CAS No.	50690-13-6
Molecular Formula	C12H15ClO
Molecular Weight	210.70 g/mol
Synonyms	2-Chloro-1-(2,3,5,6-tetramethylphenyl)ethan-1-one; 2-Chloro-1-durenyl ethanone; 2',3',5',6'-Tetramethyl-2-chloroacetophenone; 1-(Duren-2-yl)-2-chloroethanone; 50690-13-6; α-Chloro-2,3,5,6-tetramethylacetophenone; Chloromethyl 2,3,5,6-tetramethylphenyl ketone
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-1-(2,3,5,6-Tetramethylphenyl)Ethanone is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure containers are kept tightly sealed to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.