Description

4-Bromocinnamic Acid is a versatile brominated aromatic compound that serves as a key synthetic intermediate in advanced organic chemistry. Its value lies in the reactive bromine atom and the carboxylic acid functional group, which allow for selective cross-coupling reactions and further derivatization. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting inflammation, CNS disorders, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and plant growth regulators.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing brominated aromatic cores used in electronic display technologies.
• Polymer Modification: Incorporated into polymer chains to impart specific properties like flame retardancy or UV stability.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Heck, and other palladium-catalyzed coupling reactions.
• Chemical Research & Development: A standard reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating compound libraries.
• Peptide Mimetics & Bio-conjugation: The cinnamic acid structure is used to create non-natural amino acids and linking agents for bioconjugation.

Basic Information

Product Name	4-Bromocinnamic Acid
CAS No.	50663-21-3
Molecular Formula	C9H7BrO2
Molecular Weight	227.06 g/mol
Synonyms	(E)-3-(4-Bromophenyl)acrylic acid; 4-Bromocinnamic Acid; trans-4-Bromocinnamic Acid; (E)-3-(4-Bromophenyl)-2-propenoic Acid; p-Bromocinnamic Acid; 3-(4-Bromophenyl)propenoic Acid; 4-Bromo-trans-cinnamic Acid; 4-Bromobenzeneacrylic Acid
EINECS	256-674-2

Quality Control

Our 4-Bromocinnamic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	255°C - 260°C
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.