Description

α-Hydroxy-3-Nitrobenzylphosphonic Acid Diethyl Ester is a specialized organophosphorus compound that serves as a critical synthetic intermediate. Its unique structure, featuring both phosphonic ester and nitro-substituted aromatic functionalities, makes it a valuable building block for creating complex molecules with tailored properties. This chemical is essential for R&D and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop new active ingredients or functional additives.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, pesticides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for creating chelating ligands in metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of flame retardants, plasticizers, and other functional polymer additives.
• Chemical Biology Probes: Useful for constructing molecular probes to study biological processes involving phosphorylation.
• Custom Synthesis & Contract Manufacturing: A high-value intermediate for fine chemical producers serving diverse industrial R&D needs.

Basic Information

Product Name	α-Hydroxy-3-Nitrobenzylphosphonic Acid Diethyl Ester
CAS No.	50652-91-0
Molecular Formula	C11H16NO6P
Molecular Weight	289.22 g/mol
Synonyms	Diethyl (α-Hydroxy-3-nitrobenzyl)phosphonate; (3-Nitrophenyl)(hydroxy)methylphosphonic Acid Diethyl Ester; α-Hydroxy-3-nitrobenzylphosphonic Acid Diethyl Ester; Phosphonic acid, P-[(α-hydroxy-3-nitrophenyl)methyl]-, diethyl ester; Diethyl (hydroxy(3-nitrophenyl)methyl)phosphonate; (Hydroxy(3-nitrophenyl)methyl)phosphonic acid diethyl ester
EINECS	Contact for details

Quality Control

Our α-Hydroxy-3-Nitrobenzylphosphonic Acid Diethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing specific results for identity, purity, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.