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Piroctone CAS NO 50650-76-5


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CAS No.:50650-76-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Piroctone is a highly effective, broad-spectrum antimicrobial and antifungal agent belonging to the hydroxypyridone chemical class. Its primary value lies in its potent activity against Malassezia globosa, the fungus responsible for dandruff and seborrheic dermatitis, making it a cornerstone ingredient for scalp and hair health. This compound is essential for manufacturers in the personal care and cosmetic industries, specifically for formulating anti-dandruff shampoos, hair tonics, and related products. Its favorable safety profile and compatibility with other formulation ingredients further enhance its commercial utility.

Application

  • Anti-Dandruff Shampoos & Hair Care: Primary active ingredient for controlling flaking, itching, and scalp irritation associated with dandruff.
  • Scalp Treatments & Tonics: Used in leave-in formulations to provide sustained antifungal action and promote a healthy scalp environment.
  • Cosmetic Preservation: Acts as a preservative booster in rinse-off and some leave-on cosmetic products due to its efficacy against fungi and yeasts.
  • Hair Styling Products: Incorporated into gels, mousses, and sprays to prevent microbial spoilage and address scalp conditions.
  • Soaps & Cleansing Bars: Used in specialty cleansing bars designed for oily or problematic skin and scalp.
  • Veterinary Shampoos: Applied in pet care products to treat fungal skin infections and manage seborrhea in animals.

Basic Information

Product Name Piroctone
CAS No. 50650-76-5
Molecular Formula C14H23NO2
Molecular Weight 237.34 g/mol
Synonyms Piroctone Olamine; Octopirox; Piroctone Ethanolamine; 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridone, 2-aminoethanol salt; Piroctone Olamine (INCI); Piroctone Ethanolamine Salt; Piroctone Monoethanolamine Salt; Piroctone Olamine Salt
EINECS 256-599-6

Quality Control

Our Piroctone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Quality control includes comprehensive testing for identity, assay, and impurity profiles using validated methods such as HPLC and IR spectroscopy. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee compliance with your specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed after each use to prevent absorption of atmospheric moisture, which can affect stability and performance.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to reference spectrum
Assay (HPLC) 98.0% - 102.0% (on anhydrous basis)
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%
Heavy Metals (as Pb) ≤ 10 ppm
Related Substances (HPLC) Total impurities ≤ 1.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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