Description

4-Bromo-3-Chloroanisole is a halogenated anisole derivative, a versatile and high-purity organic intermediate essential for advanced chemical synthesis. Its value lies in providing a functionalized aromatic scaffold for constructing complex molecules in research and industrial applications. This compound is primarily needed by the pharmaceutical, agrochemical, and specialty chemical industries for use in the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for compounds requiring specific halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where its bromo and chloro substituents offer unique reactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic processes and material science applications.
• Organic Electronics Research: Employed in the synthesis of functionalized aromatic compounds for organic light-emitting diodes (OLEDs) and semiconductors.
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of complex colorants and specialty dyes.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.

Basic Information

Product Name	4-Bromo-3-Chloroanisole
CAS No.	50638-46-5
Molecular Formula	C7H6BrClO
Molecular Weight	221.48 g/mol
Synonyms	1-Bromo-2-chloro-4-methoxybenzene; 3-Chloro-4-bromoanisole; 2-Chloro-1-bromo-4-methoxybenzene; 4-Methoxy-2-chlorobromobenzene; Anisole, 4-bromo-3-chloro-; Benzene, 1-bromo-2-chloro-4-methoxy-; 4-Bromo-3-chloromethoxybenzene
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Chloroanisole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, and we support our clients' regulatory needs for pharmaceutical and agrochemical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.