Description

4(3H)-Quinazolinone, 2-Amino-5-Chloro- is a high-purity, heterocyclic organic compound belonging to the quinazolinone class, serving as a critical pharmaceutical intermediate. Its value lies in its role as a versatile building block for synthesizing more complex molecules with potential biological activity. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various drug candidates, particularly those targeting central nervous system disorders, inflammation, and infectious diseases.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic structure.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex heterocyclic frameworks due to its reactive amino and chloro substituents.
• Biochemical Research: Serves as a reference standard or starting material in biochemical assays and pharmacological studies.
• Material Science Exploration: Investigated for potential use in creating organic electronic materials or metal-organic frameworks (MOFs).

Basic Information

Product Name	4(3H)-Quinazolinone, 2-Amino-5-Chloro-
CAS No.	50440-85-2
Molecular Formula	C8H6ClN3O
Molecular Weight	195.61 g/mol
Synonyms	2-Amino-5-chloro-4(3H)-quinazolinone; 5-Chloro-2-amino-4(3H)-quinazolinone; 2-Amino-5-chloro-3,4-dihydroquinazolin-4-one; 5-Chloro-2-amino-3H-quinazolin-4-one; 2-Amino-5-chloroquinazolin-4(3H)-one; AQC; 5-Chloro-2-aminopteridin-4(3H)-one (incorrect but sometimes used in early literature); 50440-85-2
EINECS	Contact for details

Quality Control

Our 4(3H)-Quinazolinone, 2-Amino-5-Chloro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards for research and production use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.