Description

5-Bromo-2-Hydroxycinnamic Acid is a halogenated hydroxycinnamic acid derivative that serves as a versatile synthetic intermediate and building block in advanced organic chemistry. This compound is valued for its unique molecular structure, which incorporates both a phenolic hydroxyl group and a bromine atom on the cinnamic acid backbone, enabling selective functionalization and participation in various coupling reactions. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting inflammation, cancer, and metabolic disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive cinnamic acid core.
• Organic Synthesis: Serves as a precursor for Suzuki, Heck, and other cross-coupling reactions to create complex biaryl and conjugated systems.
• Material Science: Investigated as a monomer or additive for the synthesis of specialized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology: Employed as a probe or linker in bioconjugation strategies and the study of enzyme inhibitors.
• UV Absorber & Stabilizer Precursor: Its structure makes it a candidate for developing advanced light stabilizers for coatings and plastics.

Basic Information

Product Name	5-Bromo-2-Hydroxycinnamic Acid
CAS No.	50396-46-8
Molecular Formula	C9H7BrO3
Molecular Weight	243.06 g/mol
Synonyms	2-Hydroxy-5-bromocinnamic Acid; (E)-3-(5-Bromo-2-hydroxyphenyl)acrylic Acid; 5-Bromo-2-hydroxycinnamate; 5-Bromo-o-coumaric Acid; 3-(5-Bromo-2-hydroxyphenyl)-2-propenoic Acid; 5-Bromo-2-hydroxybenzeneacrylic Acid
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Hydroxycinnamic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.