Description

4-Chloro-6,7-Dimethoxy-2-Methylquinazoline is a high-purity, synthetically versatile quinazoline derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its functionalized structure, which provides a reactive handle for constructing complex molecules with precision. This intermediate is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex heterocyclic compounds and functional materials.
• Chemical Research: Serves as a standard or reference compound in analytical method development and metabolic studies.
• Fine Chemical Production: Integral to the multi-step synthesis of specialty chemicals used in electronics and material science.

Basic Information

Product Name	4-Chloro-6,7-Dimethoxy-2-Methylquinazoline
CAS No.	50377-49-6
Molecular Formula	C₁₁H₁₁ClN₂O₂
Molecular Weight	238.67 g/mol
Synonyms	2-Methyl-4-chloro-6,7-dimethoxyquinazoline; 4-Chloro-2-methyl-6,7-dimethoxyquinazoline; 6,7-Dimethoxy-2-methyl-4-chloroquinazoline; Quinazoline, 4-chloro-6,7-dimethoxy-2-methyl-; 50377-49-6; 4-Chloro-6,7-dimethoxy-2-methyl-quinazoline
EINECS	Contact for details

Quality Control

Our 4-Chloro-6,7-Dimethoxy-2-Methylquinazoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC/GC purity profiles, identity confirmation (IR, NMR), and impurity limits. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.