Description

8-Nitro-2,3-dihydroquinolin-4(1H)-one is a versatile nitro-substituted quinolinone derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique fused-ring structure with a nitro functional group makes it a valuable precursor for constructing complex heterocyclic systems and active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with targeted biological activities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel quinoline-based drug candidates, particularly those targeting infectious diseases or central nervous system disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging the bioactivity of the quinolinone scaffold.
• Organic Synthesis: Serves as a versatile precursor for further functionalization, including reduction of the nitro group to an amine, enabling the creation of diverse chemical libraries.
• Material Science: Potential intermediate in the synthesis of organic semiconductors, ligands for metal complexes, or dyes and pigments.
• Academic & Contract Research: A valuable reagent for methodological studies and the discovery of new chemical reactions in university and CRO laboratory settings.

Basic Information

Product Name	8-Nitro-2,3-dihydroquinolin-4(1H)-one
CAS No.	50349-89-8
Molecular Formula	C9H8N2O3
Molecular Weight	192.17 g/mol
Synonyms	8-Nitro-1,2,3,4-tetrahydro-4-oxoquinoline; 8-Nitro-1,2,3,4-tetrahydroquinolin-4-one; 8-Nitro-3,4-dihydro-2H-quinolin-4-one; 8-Nitro-2,3-dihydro-4(1H)-quinolinone; 4(1H)-Quinolinone, 8-nitro-2,3-dihydro-; 8-Nitro-1,2,3,4-tetrahydro-4-quinolone
EINECS	Contact for details

Quality Control

Our 8-Nitro-2,3-dihydroquinolin-4(1H)-one is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.