Description

6-Chloro-4-Phenyl Quinazoline-2-Carboxylic Acid is a high-purity, versatile quinazoline derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various quinazoline-based drug candidates, particularly those targeting kinase inhibition.
• Agrochemical Research: Used in the development of novel herbicides and fungicides, leveraging its heterocyclic core structure.
• Organic Synthesis Building Block: Serves as a versatile scaffold for constructing complex molecules in medicinal and combinatorial chemistry.
• Material Science Research: Investigated as a potential monomer or additive for creating advanced polymers with specific electronic or optical properties.
• Biochemical Tool Compound: Utilized in biochemical assays and as a reference standard in analytical laboratories.

Basic Information

Product Name	6-Chloro-4-Phenyl Quinazoline-2-Carboxylic Acid
CAS No.	5958-08-7
Molecular Formula	C15H9ClN2O2
Molecular Weight	284.70 g/mol
Synonyms	2-Quinazolinecarboxylic acid, 6-chloro-4-phenyl-; 6-Chloro-4-phenylquinazoline-2-carboxylic acid; 4-Phenyl-6-chloroquinazoline-2-carboxylic acid; 6-Chloro-4-phenyl-2-quinazolinecarboxylic acid; 6-Chloro-4-phenylquinoline-2-carboxylic acid (common misnomer); 6-Cl-4-Ph-Quin-2-COOH (abbreviation); 5958-08-7 (CAS registry)
EINECS	Contact for details

Quality Control

Our 6-Chloro-4-Phenyl Quinazoline-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be stored away from direct light exposure. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.