Description

6-Chloro-4-Phenylquinazolin-2-Carboxaldehyde is a versatile and high-value quinazoline derivative, serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both a chloro substituent and a reactive aldehyde group, makes it an indispensable intermediate for constructing complex heterocyclic systems. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential kinase inhibitors, anticancer agents, and other biologically active quinazoline-based compounds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the quinazoline scaffold.
• Material Science: Serves as a building block for creating organic ligands in coordination chemistry and for synthesizing advanced organic electronic materials.
• Chemical Synthesis: The reactive aldehyde group facilitates further functionalization through condensation, reduction, or nucleophilic addition reactions, enabling the creation of diverse chemical libraries.
• Academic & R&D: Widely used in university and industrial research laboratories for methodological studies and exploring new reaction pathways in heterocyclic chemistry.

Basic Information

Product Name	6-Chloro-4-Phenylquinazolin-2-Carboxaldehyde
CAS No.	5958-05-4
Molecular Formula	C15H9ClN2O
Molecular Weight	268.70 g/mol
Synonyms	2-Formyl-6-chloro-4-phenylquinazoline; 6-Chloro-4-phenyl-2-quinazolinecarboxaldehyde; 4-Phenyl-6-chloroquinazoline-2-carbaldehyde; Quinazoline-2-carboxaldehyde, 6-chloro-4-phenyl-; 6-Chloro-4-phenylquinazoline-2-carbaldehyde; 6-Chloro-4-phenyl-2-quinazolinecarbaldehyde
EINECS	Contact for details

Quality Control

Our 6-Chloro-4-Phenylquinazolin-2-Carboxaldehyde is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing all specifications is supplied with each shipment, ensuring full traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, it is recommended to handle under an inert atmosphere for long-term storage and to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.