Description

3-Chloro-3-Methylbutanone is a versatile chlorinated ketone intermediate with significant utility in advanced organic synthesis. Its value lies in its reactive carbonyl and chloromethyl groups, enabling it to serve as a key building block for pharmaceuticals, agrochemicals, and specialty materials. This compound is essential for R&D chemists and process development teams in the fine chemical, pharmaceutical, and crop protection industries seeking to introduce specific functional groups into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring chlorinated side chains or specific ketone functionalities.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and insecticides, where its structure contributes to the biological activity of the final product.
• Organic Synthesis Building Block: Employed in various name reactions and coupling processes to construct more complex organic molecules in research and development.
• Polymer & Resin Modifier: Acts as a reactive monomer or cross-linking agent in the production of specialty polymers, coatings, and adhesives to alter physical properties.
• Flavor & Fragrance Ingredient Synthesis: Serves as an intermediate for creating specific aroma chemicals and flavor compounds.
• Chemical Research & Development: A valuable reagent for methodological studies and exploring new synthetic pathways in academic and industrial laboratories.

Basic Information

Product Name	3-Chloro-3-Methylbutanone
CAS No.	5950-19-6
Molecular Formula	C5H9ClO
Molecular Weight	120.58 g/mol
Synonyms	3-Chloro-3-methylbutan-2-one; 1-Chloro-1,1-dimethylacetone; 3-Chloropivalaldehyde; 3-Chloro-3-methyl-2-butanone; Chloropinacolone; Pivaloyl chloride, reduced; 1-Chloro-2,2-dimethyl-3-butanone; 3-Methyl-3-chlorobutanone
EINECS	227-724-7

Quality Control

Our 3-Chloro-3-Methylbutanone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring the material meets the rigorous standards required for synthesis and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatility loss.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.435 - 1.445
Density (20°C)	1.05 - 1.10 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.