Description

Methyl 2-(Aminooxy)Acetate Hydrochloride is a versatile chemical building block and reagent, primarily valued for its unique aminooxy functional group. This compound is essential for the synthesis of oxime ethers and other conjugates, enabling critical bioconjugation and linker chemistry in advanced research and manufacturing. It is particularly sought after by pharmaceutical researchers, agrochemical developers, and fine chemical manufacturers for creating novel active ingredients and diagnostic probes.

Application

• Pharmaceutical Intermediates: Key reagent in the synthesis of oxime-based prodrugs, antibody-drug conjugates (ADCs), and targeted therapeutic agents.
• Bioconjugation Chemistry: Used for site-specific labeling of proteins, peptides, and antibodies via reaction with carbonyl groups (aldehydes and ketones).
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and plant growth regulators with enhanced properties.
• Polymer Modification: Functional monomer for introducing reactive aminooxy groups into polymer backbones for advanced material science applications.
• Diagnostic Reagents: Component in the development of immunoassay kits and biosensors for clinical and research diagnostics.
• Cross-linking Agent: Facilitates the cross-linking of biomolecules and materials in biotechnological and nanotechnology applications.
• Chemical Biology Probes: Enables the study of protein function and interaction through selective labeling strategies.

Basic Information

Product Name	Methyl 2-(Aminooxy)Acetate Hydrochloride
CAS No.	5940-07-8
Molecular Formula	C3H8ClNO3
Molecular Weight	141.55 g/mol
Synonyms	Methyl (Aminooxy)acetate hydrochloride; O-Methylhydroxylamine-O-acetic acid hydrochloride; Aminooxyacetic acid methyl ester hydrochloride; Methyl glycolyloxyamine hydrochloride; Methyl 2-(hydroxyamino)acetate hydrochloride; (Methoxycarbonylmethyl)hydroxylamine hydrochloride; Acetic acid, 2-(aminooxy)-, methyl ester, hydrochloride
EINECS	Contact for details

Quality Control

Our Methyl 2-(Aminooxy)Acetate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.