Description

Metamizole Sodium Monohydrate CAS NO 5907-38-0 is a non-opioid analgesic and antipyretic agent belonging to the pyrazolone class. It is a critical active pharmaceutical ingredient (API) valued for its potent pain-relieving and fever-reducing properties. This compound is primarily required by pharmaceutical manufacturers for the formulation of injectable and oral analgesic medications.

Application

• Primary Active Pharmaceutical Ingredient (API) in analgesic and antipyretic drug formulations.
• Manufacturing of injectable solutions for postoperative and severe pain management.
• Production of oral dosage forms such as tablets and powders for general pain relief.
• Key component in combination drug therapies for enhanced therapeutic effects.
• Used in veterinary medicine for pain and fever control in animals.
• Intermediate in the synthesis of more complex pharmaceutical compounds.
• Reference standard in analytical laboratories for quality control and research.

Basic Information

Product Name	Metamizole Sodium Monohydrate
CAS No.	5907-38-0
Molecular Formula	C13H16N3NaO4S • H2O
Molecular Weight	351.35 g/mol
Synonyms	Dipyrone Monohydrate; Sodium [(2,3-Dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methanesulfonate Monohydrate; Noramidopyrine Methanesulfonate Sodium Monohydrate; Analgin; Novalgin; Metamizol Sodium Monohydrate; Metamizolum Natricum Monohydricum
EINECS	227-614-1

Quality Control

Our Metamizole Sodium Monohydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity pharmacopeial standards (such as USP/EP). A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.5% - 101.0% (on anhydrous basis)
Water Content (KF)	4.5% - 5.5%
Related Substances (HPLC)	Total impurities ≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
pH (5% solution)	6.0 - 7.5
Microbial Enumeration	Meets EP/USP criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.