Description

2,5-Dichloro-4-Nitrophenol is a versatile halogenated nitrophenol derivative, serving as a critical synthetic intermediate in advanced chemical manufacturing. Its value lies in the strategic positioning of its functional groups, which enable precise chemical transformations for creating complex molecules. This compound is essential for research and production facilities in the pharmaceutical, agrochemical, and dye industries, where it is used to build active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a halogenated phenolic core.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and pesticides, where the nitro and chloro groups contribute to biological activity.
• Dye and Pigment Manufacturing: Serves as a precursor for azo dyes and other complex colorants, providing chromophore and auxochrome elements.
• Chemical Research & Development: Employed in organic synthesis laboratories for studying electrophilic aromatic substitution and nucleophilic displacement reactions.
• Polymer Modifier: Can be used to introduce functional phenolic groups into polymer chains to alter material properties.
• Cross-coupling Reagent: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for creating biaryl structures.

Basic Information

Product Name	2,5-Dichloro-4-Nitrophenol
CAS No.	5847-57-4
Molecular Formula	C6H3Cl2NO3
Molecular Weight	208.00 g/mol
Synonyms	4-Nitro-2,5-dichlorophenol; 2,5-Dichloro-4-nitro-phenol; Phenol, 2,5-dichloro-4-nitro-; 2,5-Dichloro-4-hydroxy-nitrobenzene; NSC 403107; 2,5-Dichloro-4-nitrophenol (6CI,7CI,8CI); 2,5-Dichloro-4-nitro-1-hydroxybenzene
EINECS	227-448-1

Quality Control

Our 2,5-Dichloro-4-Nitrophenol is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets exacting standards for use in sensitive synthesis applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in a dark place.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	118°C - 122°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.