Description

2-Azabicyclo[2.2.2]octane hydrochloride is a versatile bicyclic amine hydrochloride salt, valued for its rigid, three-dimensional scaffold. This compound is a crucial building block and intermediate in advanced organic synthesis, particularly for pharmaceuticals and agrochemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for neurological and cardiovascular targets.
• Ligand and Catalyst Synthesis: Used to create chiral amines and ligands for asymmetric catalysis and metal complexation.
• Agrochemical Research: Serves as a core structure in developing novel herbicides, fungicides, and plant growth regulators.
• Material Science: Building block for polymers and advanced materials requiring rigid, nitrogen-containing heterocycles.
• Chemical Biology & Proteomics: Useful as a molecular scaffold or tag in probe and inhibitor design for biological studies.
• Academic & Industrial R&D: Fundamental research reagent for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	2-Azabicyclo[2.2.2]octane hydrochloride
CAS No.	5845-15-8
Molecular Formula	C7H14ClN
Molecular Weight	147.65 g/mol
Synonyms	2-Azabicyclo[2.2.2]octane, hydrochloride; 2-Azabicyclo[2.2.2]octane HCl; Quinuclidine hydrochloride; 1-Azabicyclo[2.2.2]octane hydrochloride (common misnomer); ABCO hydrochloride; Bicyclo[2.2.2]octan-2-amine hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Azabicyclo[2.2.2]octane hydrochloride is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request, supporting compliance in cGMP and ISO environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.