Description

2-Methylenequinuclidin-3-One Hydrochloride is a specialized bicyclic organic compound in its hydrochloride salt form, offering enhanced stability and handling properties. This high-purity intermediate is critical for research and development in advanced pharmaceutical synthesis, particularly for its role as a key building block in complex molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and exploring new synthetic pathways.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of complex drug candidates, particularly those targeting neurological and cardiovascular pathways.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that require specific bicyclic amine structures.
• Fine Chemical Synthesis: Serves as a versatile precursor for creating specialty chemicals, catalysts, and ligands used in asymmetric synthesis.
• Academic & Institutional R&D: Employed in university and research institute laboratories for methodological studies and the exploration of new organic reactions.
• Process Chemistry Development: Utilized for scaling up synthetic routes from laboratory to pilot plant and commercial production.

Basic Information

Product Name	2-Methylenequinuclidin-3-One Hydrochloride
CAS No.	5832-54-2
Molecular Formula	C8H12ClNO
Molecular Weight	173.64 g/mol
Synonyms	3-Quinuclidinone, 2-methylene-, hydrochloride; 2-Methylene-3-quinuclidinone hydrochloride; 2-Methylenequinuclidin-3-one HCl; 3-Quinuclidinone, 2-methylidene-, hydrochloride; 2-Methylidenequinuclidin-3-one hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Methylenequinuclidin-3-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.