Description

6-Bromo-2-Naphthoic Acid is a versatile brominated naphthalene derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its functionalized aromatic structure, which allows for selective cross-coupling reactions and further derivatization, making it indispensable for creating complex molecular architectures. This high-purity intermediate is primarily needed by pharmaceutical R&D teams, agrochemical manufacturers, and specialty chemical companies developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs) and other active pharmaceutical ingredients (APIs) targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where the bromine atom allows for efficient structural modification.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis for fine chemical production.
• Material Science Research: Employed in the creation of organic semiconductors, liquid crystals, and photoactive polymers due to its rigid, planar naphthalene core.
• Dyestuff and Pigment Manufacturing: Acts as an intermediate for producing high-performance, light-fast azo dyes and organic pigments.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, particularly in Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions.

Basic Information

Product Name	6-Bromo-2-Naphthoic Acid
CAS No.	5773-80-8
Molecular Formula	C11H7BrO2
Molecular Weight	251.08 g/mol
Synonyms	2-Naphthoic acid, 6-bromo-; 6-Bromo-2-naphthalenecarboxylic acid; 6-Bromonaphthalene-2-carboxylic acid; 2-Carboxy-6-bromonaphthalene; NSC 404124; 6-Br-2-NA; 6-Bromo-β-naphthoic acid
EINECS	227-307-6

Quality Control

Our 6-Bromo-2-Naphthoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	248°C - 252°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.