Description

7-Bromo-2,3-Dihydro-1,4-Benzoxazepin-5(4H)-One is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. Its core benzoxazepinone scaffold, functionalized with a reactive bromine atom, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to its benzoxazepine core.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the bromine atom allows for further functionalization to optimize biological activity.
• Material Science: Acts as a monomer or building block for creating specialized polymers and organic electronic materials with unique properties.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the benzoxazepinone moiety into more complex molecules.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological studies and the exploration of new chemical spaces in medicinal chemistry.

Basic Information

Product Name	7-Bromo-2,3-Dihydro-1,4-Benzoxazepin-5(4H)-One
CAS No.	5755-05-5
Molecular Formula	C9H8BrNO2
Molecular Weight	242.07 g/mol
Synonyms	7-Bromo-2,3,4,5-tetrahydro-1,4-benzoxazepin-5-one; 7-Bromo-4,5-dihydro-1,4-benzoxazepin-5(3H)-one; 7-Bromo-2,3-dihydro-1,4-benzoxazepin-5-one; 7-Bromo-4,5-dihydro-3H-1,4-benzoxazepin-5-one; 4,5-Dihydro-7-bromo-3H-1,4-benzoxazepin-5-one; 7-Bromo-4,5-dihydrobenzo[f][1,4]oxazepin-5(3H)-one
EINECS	Contact for details

Quality Control

Our 7-Bromo-2,3-Dihydro-1,4-Benzoxazepin-5(4H)-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.