Description

3-Iodobiphenyl-4-Carboxylic Acid is a high-purity iodinated biphenyl derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid group and an iodine atom on the biphenyl scaffold, makes it an invaluable intermediate for constructing complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as Suzuki-Miyaura cross-coupling reactions and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in the development of novel herbicides and fungicides, leveraging the biphenyl core for biological activity.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and liquid crystals.
• Cross-Coupling Reactions: The iodine atom acts as an excellent handle for palladium-catalyzed cross-coupling, such as Suzuki, Heck, and Sonogashira reactions, to form biaryl systems.
• Ligand Synthesis: Utilized for preparing sophisticated ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein functions.

Basic Information

Product Name	3-Iodobiphenyl-4-Carboxylic Acid
CAS No.	5737-84-8
Molecular Formula	C13H9IO2
Molecular Weight	324.12 g/mol
Synonyms	4'-Iodo-[1,1'-biphenyl]-4-carboxylic acid; 4-Carboxy-4'-iodobiphenyl; 3-Iodobiphenyl-4-carboxylic acid; [1,1'-Biphenyl]-4-carboxylic acid, 4'-iodo-; 4'-Iodobiphenyl-4-carboxylic Acid; Biphenyl-4-carboxylic acid, 4'-iodo-; 4-Iodobiphenyl-4'-carboxylic Acid (alternate numbering)
EINECS	Contact for details

Quality Control

Every batch of 3-Iodobiphenyl-4-Carboxylic Acid is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.