Description

4'-Fluoro-Biphenyl-4-Carboxylic Acid is a high-purity fluorinated biphenyl derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which combines a carboxylic acid functional group with a fluorinated aromatic system, enabling precise modifications in target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in therapeutic areas like oncology and inflammation.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators where the fluorine atom enhances bioactivity and stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystal compounds for display technologies.
• Organic Electronic Materials: Employed in the development of organic semiconductors and charge-transport materials for OLEDs and photovoltaics.
• Cross-Coupling Reactions: Acts as a versatile substrate in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D focused on fluorochemistry and medicinal chemistry.

Basic Information

Product Name	4'-Fluoro-Biphenyl-4-Carboxylic Acid
CAS No.	5731-10-2
Molecular Formula	C13H9FO2
Molecular Weight	216.21 g/mol
Synonyms	4'-Fluoro[1,1'-biphenyl]-4-carboxylic acid; 4-(4-Fluorophenyl)benzoic acid; p-Fluorobiphenyl-4'-carboxylic acid; [1,1'-Biphenyl]-4-carboxylic acid, 4'-fluoro-; 4-Carboxy-4'-fluorobiphenyl; 4-Fluoro-4'-biphenylcarboxylic Acid; Biphenyl-4-carboxylic acid, 4'-fluoro-
EINECS	227-247-6

Quality Control

Our 4'-Fluoro-Biphenyl-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the high standards required for research and cGMP manufacturing applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Melting Point	245 - 250 °C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.