Description

2-[(S)-1-Oxo-2-[[(Benzyloxy)Carbonyl]Amino]Propyl]Hydrazine-1-Carboxylic Acid tert-Butyl Ester is a sophisticated chiral building block and protected amino acid derivative essential for advanced organic synthesis. This compound is valued for its role in constructing complex peptide backbones and heterocyclic structures with high stereochemical fidelity. It is primarily utilized by research institutions and pharmaceutical manufacturers in the development of novel active pharmaceutical ingredients (APIs), peptide-based therapeutics, and specialized fine chemicals.

Application

• Peptide Synthesis: A key chiral intermediate for the solid-phase and solution-phase synthesis of complex peptides and peptidomimetics.
• Pharmaceutical Research: Used in the research and development of new drug candidates, particularly in oncology and metabolic disease pathways.
• API Manufacturing: Serves as a critical building block in the multi-step synthesis of advanced active pharmaceutical ingredients (APIs).
• Chemical Biology: Employed in the synthesis of probes and labeled compounds for studying biological mechanisms and protein interactions.
• Heterocyclic Chemistry: A precursor for the synthesis of various nitrogen-containing heterocycles, which are common scaffolds in medicinal chemistry.
• Custom Synthesis: A valuable starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke fine chemicals.

Basic Information

Product Name	2-[(S)-1-Oxo-2-[[(Benzyloxy)Carbonyl]Amino]Propyl]Hydrazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	5721-18-6
Molecular Formula	C16H23N3O5
Molecular Weight	337.37 g/mol
Synonyms	N-[(Benzyloxy)carbonyl]-L-alanine tert-butyl hydrazide; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-N-(tert-butoxycarbonyl)propanehydrazide (common research context); Boc-NH-NH-CO-L-Ala-Z; Z-L-Ala-NH-NH-Boc; tert-Butyl (2S)-2-[[(benzyloxy)carbonyl]amino]propanehydrazocarboxylate; L-Alanine, N-[(phenylmethoxy)carbonyl]-, 1,1-dimethylethyl hydrazide; N-Cbz-L-alanine tert-butyl hydrazide.
EINECS	Contact for details

Quality Control

Our production of 2-[(S)-1-Oxo-2-[[(Benzyloxy)Carbonyl]Amino]Propyl]Hydrazine-1-Carboxylic Acid tert-Butyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.