Description

trans-2-Aminomethyl-1-Cyclohexanol is a versatile chiral amino alcohol building block of significant synthetic importance. Its bifunctional structure, featuring both a primary amine and a secondary alcohol group on a rigid cyclohexane scaffold, makes it a valuable intermediate for constructing complex molecules with defined stereochemistry. This compound is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as asymmetric synthesis, chiral ligand preparation, and the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Catalyst & Ligand Precursor: Used to develop novel chiral ligands and organocatalysts for enantioselective transformations in fine chemical synthesis.
• Agrochemical Synthesis: Serves as a building block for creating chiral active ingredients in herbicides, fungicides, and plant growth regulators.
• Corrosion Inhibitor Formulation: Employed in the development of advanced, environmentally friendly corrosion inhibitors for industrial water treatment and metalworking fluids.
• Polymer Modification: Acts as a monomer or cross-linking agent for producing specialty polymers with enhanced thermal stability or specific functional groups.
• Research & Development: A valuable standard and starting material in academic and industrial R&D for exploring new synthetic methodologies and bioactive compounds.

Basic Information

Product Name	trans-2-Aminomethyl-1-Cyclohexanol
CAS No.	5691-09-8
Molecular Formula	C7H15NO
Molecular Weight	129.20 g/mol
Synonyms	(1R,2S)-2-(Aminomethyl)cyclohexanol; (1S,2R)-2-(Aminomethyl)cyclohexanol; trans-2-(Aminomethyl)cyclohexan-1-ol; 2-(Aminomethyl)cyclohexanol; 2-Cyclohexanol, 1-(aminomethyl)-, trans-; 1-Amino-2-hydroxycyclohexanemethane; NSC 403697
EINECS	Contact for details

Quality Control

Our trans-2-Aminomethyl-1-Cyclohexanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity determination, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC/GC), chiral excess, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation and maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (trans-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.