Description

Glycine Methyl Ester Hydrochloride is a protected amino acid derivative essential for advanced organic synthesis. This compound serves as a critical building block for the controlled introduction of the glycine moiety, enabling the production of complex peptides and fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and biotechnology sectors for applications ranging from drug discovery to material science.

Application

• Pharmaceutical Intermediates: Key starting material and building block in the synthesis of peptide-based drugs, active pharmaceutical ingredients (APIs), and novel therapeutic compounds.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) as a protected glycine derivative to construct specific peptide sequences.
• Agrochemical Research: Intermediate in the development of herbicides, pesticides, and plant growth regulators that incorporate amino acid structures.
• Bioconjugation & Linker Chemistry: Employed in the preparation of chemical linkers and for bioconjugation strategies in antibody-drug conjugates (ADCs) and diagnostic agents.
• Biochemical Research: Tool compound in enzymatic studies and for the preparation of customized amino acid analogs in metabolic pathway research.
• Fine Chemical Synthesis: Versatile reagent for the synthesis of complex organic molecules, heterocycles, and specialty chemicals requiring protected amino functionality.

Basic Information

Product Name	Glycine Methyl Ester Hydrochloride
CAS No.	5680-79-5
Molecular Formula	C3H8ClNO2
Molecular Weight	125.55 g/mol
Synonyms	Methyl glycinate hydrochloride; Glycine methyl ester HCl; H-Gly-OMe·HCl; 2-Aminoacetic acid methyl ester hydrochloride; Methyl aminoacetate hydrochloride; Glycine methyl ester monohydrochloride; Methyl 2-aminoacetate hydrochloride; Aminoacetic acid methyl ester hydrochloride
EINECS	227-123-7

Quality Control

Our Glycine Methyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	175°C - 185°C
Water Content (KF)	≤1.0%
Heavy Metals (as Pb)	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.