Description

Tyvelose is a unique deoxy sugar, specifically 3,6-dideoxy-D-mannose, with the CAS registry number 5658-12-8. This compound is a critical antigenic determinant found in the O-antigens of certain Gram-negative bacteria, making it a vital tool in immunological research and diagnostics. It is primarily utilized by researchers and manufacturers in the life sciences sector for the study of bacterial pathogenesis, vaccine development, and the production of specific antibodies. Its role as a hapten and a defined carbohydrate antigen is essential for advancing our understanding of host-pathogen interactions.

Application

• Immunological Research: As a defined hapten for studying antibody-antigen interactions and immune responses.
• Vaccine Development: Used in the research and synthesis of conjugate vaccines targeting specific bacterial serotypes.
• Diagnostic Reagent Production: Serves as a key component in the manufacture of immunoassays and diagnostic kits for bacterial identification.
• Glycobiology Studies: A valuable standard and building block for investigating carbohydrate chemistry and biosynthesis pathways.
• Antibody Generation: Employed to raise monoclonal and polyclonal antibodies for research and therapeutic applications.
• Microbiology Reference Standard: Used as a pure chemical standard in laboratories for quality control and method validation.

Basic Information

Product Name	Tyvelose
CAS No.	5658-12-8
Molecular Formula	C6H12O4
Molecular Weight	148.16 g/mol
Synonyms	3,6-Dideoxy-D-mannose; D-Tyvelose; Tyvelose; Abequose isomer; 3,6-Dideoxymannose; Paratose isomer; (2R,4S,5R)-2,4,5-Trihydroxy-3,6-dioxohexanal (tautomeric form); Antigenic sugar O:9
EINECS	227-112-2

Quality Control

Every batch of Tyvelose is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency suitable for research applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing specific analytical results, including assay, optical rotation, and impurity profiles, are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic nature, this product should be stored in a cool, dry place, ideally at controlled room temperature (15-25°C). For long-term stability, consider storage under an inert atmosphere or with desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Optical Rotation	+25° to +30° (c=1 in H2O)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.