Description

2-Chloro-1,3,2-Oxazaphosphacyclohexane 2-Oxide is a specialized organophosphorus compound that serves as a key intermediate in advanced chemical synthesis. Its unique heterocyclic structure, containing both phosphorus and nitrogen, makes it a valuable precursor for the development of pharmaceuticals, agrochemicals, and flame retardants. This high-purity intermediate is essential for research institutions and industrial manufacturers engaged in creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in the development of antiviral and anticancer agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators.
• Flame Retardant Precursor: Serves as a key intermediate in manufacturing phosphorus-based flame retardants for polymers and textiles.
• Ligand and Catalyst Development: Employed in organometallic chemistry for creating specialized ligands and catalysts.
• Chemical Research: A valuable reagent for academic and industrial R&D in heterocyclic and organophosphorus chemistry.
• Material Science: Used in the synthesis of functional materials and specialty polymers.

Basic Information

Product Name	2-Chloro-1,3,2-Oxazaphosphacyclohexane 2-Oxide
CAS No.	5638-58-4
Molecular Formula	C4H9ClNO2P
Molecular Weight	169.55 g/mol
Synonyms	2-Chloro-2-oxo-1,3,2-oxazaphosphorinane; 2-Chloro-1,3,2-oxazaphosphorinane 2-oxide; NSC 163049; 1,3,2-Oxazaphosphorinane, 2-chloro-2-oxo-; 2-Chloro-2-oxo-1,3,2-oxazaphosphacyclohexane; Cyclophosphamide Impurity; Phosphoramide acid, (2-chloro-1,3,2-oxazaphosphorinanyl)-, P-oxide
EINECS	227-077-5

Quality Control

Our 2-Chloro-1,3,2-Oxazaphosphacyclohexane 2-Oxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.