Description

1,2-Bis(Aminooxy)Ethane CAS NO 5627-11-2 is a versatile bifunctional aminooxy compound, serving as a critical building block and cross-linking agent in advanced organic synthesis. Its primary value lies in its ability to form stable oxime bonds with carbonyl groups, enabling precise bioconjugation and material functionalization. This chemical is essential for researchers and manufacturers in the pharmaceutical, biotech, and polymer industries who require reliable, high-purity intermediates for developing novel therapeutics, diagnostics, and specialty materials.

Application

• Bioconjugation Reagent: For site-specific labeling of proteins, antibodies, and peptides with fluorophores, drugs, or other biomolecules via oxime ligation.
• Polymer Cross-Linker: Used in the synthesis of hydrogels, dendrimers, and functional polymers to introduce aminooxy functionality and control network properties.
• Pharmaceutical Intermediate: Serves as a key synthon in the development of active pharmaceutical ingredients (APIs) and prodrugs.
• Surface Functionalization: Modifies surfaces of nanoparticles, chips, or resins to create reactive platforms for biosensor and diagnostic assay development.
• Carbohydrate Chemistry: Employed in the chemoselective modification of sugars and glycoconjugates.
• Material Science Research: A valuable tool for creating novel smart materials and studying polymer network formation.

Basic Information

Product Name	1,2-Bis(Aminooxy)Ethane
CAS No.	5627-11-2
Molecular Formula	C4H12N2O2
Molecular Weight	120.15 g/mol
Synonyms	Ethane-1,2-diamine, N,N'-dihydroxy-; 1,2-Ethanediamine, N,N'-dihydroxy-; N,N'-Dihydroxy-1,2-ethanediamine; N,N'-Dihydroxyethylenediamine; 1,2-Diaminooxyethane; Aminooxy crosslinker; Bis-aminooxyethane; O,O'-(Ethane-1,2-diyl) dihydroxylamine
EINECS	227-062-6

Quality Control

Our 1,2-Bis(Aminooxy)Ethane is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, NMR, and titration, to verify identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.