Description

L-Alanine Benzyl Ester Hydrochloride is a protected amino acid derivative essential for peptide synthesis and pharmaceutical research. This compound serves as a crucial chiral building block, enabling the controlled introduction of the alanine moiety into complex molecular structures while preventing unwanted side reactions. It is primarily utilized by research institutions, pharmaceutical development labs, and fine chemical manufacturers engaged in the production of active pharmaceutical ingredients (APIs), peptide hormones, and other biologically active compounds.

Application

• Peptide Synthesis: A key intermediate in solid-phase and solution-phase peptide synthesis for constructing peptide chains.
• Pharmaceutical Intermediates: Used in the research and development of novel therapeutic agents and APIs.
• Bioconjugation: Acts as a linker or spacer molecule in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Organic Synthesis: Serves as a chiral synthon in asymmetric synthesis and the preparation of non-peptide small molecules.
• Biochemical Research: Employed in enzymatic studies and as a substrate analog in metabolic pathway investigations.
• Protecting Group Chemistry: The benzyl ester group provides temporary protection for the carboxylic acid functionality, which can be selectively removed under specific conditions.

Basic Information

Product Name	L-Alanine Benzyl Ester Hydrochloride
CAS No.	5557-83-5
Molecular Formula	C10H14ClNO2
Molecular Weight	215.68 g/mol
Synonyms	L-Alanine benzyl ester hydrochloride; (S)-2-Aminopropanoic acid benzyl ester hydrochloride; H-Ala-OBzl·HCl; Benzyl L-alaninate hydrochloride; Alanine benzyl ester HCl; L-2-Aminopropionic acid benzyl ester hydrochloride; (S)-Benzyl 2-aminopropanoate hydrochloride; NSC 3349
EINECS	226-914-5

Quality Control

Our L-Alanine Benzyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and pharmaceutical applications. Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Melting Point	Contact for details
Loss on Drying	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.