Description

n-Vanillyl-10-Undecenylamide is a synthetic capsaicinoid, a non-pungent analog of capsaicin. This compound is valued for its potent and selective activity as a TRPV1 (Transient Receptor Potential Vanilloid 1) agonist, making it a critical research tool and a key ingredient in specialized formulations. It is primarily sought by the pharmaceutical, nutraceutical, and advanced materials sectors for applications requiring targeted activation of the vanilloid receptor pathway without the associated heat sensation.

Application

• Pharmaceutical Research & Development: A standard reference compound and active agent for studying TRPV1 receptor function, pain pathways, and neurogenic inflammation.
• Topical Analgesic Formulations: Used in the development of creams, gels, and patches designed for targeted pain relief without causing skin irritation or a burning sensation.
• Nutraceutical & Cosmetic Ingredients: Incorporated into formulations for its potential anti-inflammatory and circulation-enhancing properties in cosmeceuticals and dietary supplements.
• Neuroscience & Cell Biology: Essential for in vitro and in vivo studies investigating sensory neuron activation, calcium signaling, and thermal regulation mechanisms.
• Chemical Synthesis Intermediate: Serves as a building block for the synthesis of more complex vanilloid derivatives and novel TRP channel modulators.
• Functional Material Science: Investigated for use in smart materials and sensors that respond to specific biochemical triggers via the TRPV1 pathway.

Basic Information

Product Name	n-Vanillyl-10-Undecenylamide
CAS No.	5555-46-4
Molecular Formula	C19H29NO3
Molecular Weight	319.44 g/mol
Synonyms	10-Undecenyl vanillylamide; N-Vanillyl-10-undecenamide; Capsaicin analog (non-pungent); Nonivamide derivative; Synthetic capsaicinoid; (E)-N-(4-Hydroxy-3-methoxybenzyl)undec-10-enamide; Olvanil analog; TRPV1 agonist (reference standard)
EINECS	Contact for details

Quality Control

Our n-Vanillyl-10-Undecenylamide is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for research and formulation. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a low-humidity environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.