Description

6-Iodoquinolin-8-Amine is a halogenated quinoline derivative serving as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its core value lies in the strategic positioning of the iodine and amine functional groups, enabling precise cross-coupling reactions and derivatization for complex molecule construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in oncology and antimicrobial research.
• Agrochemical Research: Used in creating novel fungicides, herbicides, and insecticides by leveraging the quinoline scaffold.
• Material Science Precursor: Serves as a starting material for synthesizing organic ligands used in catalysis and functional materials.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig amination.
• Chemical Biology Probes: Utilized in developing fluorescent markers or molecular probes for biochemical assays.
• Academic & R&D: Fundamental research reagent in organic synthesis and methodology development within university and industrial laboratories.

Basic Information

Product Name	6-Iodoquinolin-8-Amine
CAS No.	5552-47-6
Molecular Formula	C9H7IN2
Molecular Weight	270.07 g/mol
Synonyms	8-Amino-6-iodoquinoline; 6-Iodo-8-aminoquinoline; Quinoline, 8-amino-6-iodo-; 8-Quinolinamine, 6-iodo-; 6-Iodo-8-quinolinamine
EINECS	Contact for details

Quality Control

Our 6-Iodoquinolin-8-Amine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, NMR, and mass spectrometry, for comprehensive characterization and impurity profiling. A Certificate of Analysis (COA) detailing purity, identity, and related substances is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Light yellow to brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.