Description

6-Iodo-8-Nitroquinoline is a halogenated nitroquinoline derivative that serves as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its unique structure, combining an iodine substituent with a nitro group on the quinoline scaffold, makes it a critical building block for constructing complex molecules with tailored electronic and biological properties. This compound is primarily sought after by research institutions and pharmaceutical developers for applications in medicinal chemistry, materials science, and agrochemical research.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel quinoline-based drug candidates, particularly for antimicrobial, anticancer, and antimalarial research.
• Agrochemical Development: Used in creating advanced active ingredients for crop protection products, leveraging its halogenated structure for enhanced bioactivity.
• Material Science Research: Serves as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) where the iodine atom acts as an excellent leaving group for introducing diverse functional groups.
• Dye and Pigment Industry: Intermediate for synthesizing specialized heterocyclic dyes and colorants due to the nitroquinoline core.
• Academic & R&D: A valuable reagent for methodological studies in organic synthesis and for investigating structure-activity relationships (SAR).

Basic Information

Product Name	6-Iodo-8-Nitroquinoline
CAS No.	5552-46-5
Molecular Formula	C9H5IN2O2
Molecular Weight	300.05 g/mol
Synonyms	8-Nitro-6-iodoquinoline; 6-Iodo-8-nitro-quinoline; Quinoline, 6-iodo-8-nitro-; 6-Iodo-8-nitro-chinolin; 6-Iodo-8-nitro-chinoline; 6-Iodo-8-nitro-chinolina
EINECS	Contact for details

Quality Control

Our 6-Iodo-8-Nitroquinoline is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity (by HPLC), identity confirmation, and impurity profiles. Our quality system is designed to meet the stringent requirements of pharmaceutical and advanced material research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to protect from moisture and contamination. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.