Description

p-Nitrophenylvinyl Sulfone is a specialized organic compound featuring a reactive vinyl sulfone group. This chemical is valued for its role as a versatile building block and cross-linking agent in advanced organic synthesis. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing novel compounds and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of active pharmaceutical ingredients (APIs), particularly for targeted drug conjugates.
• Bioconjugation Reagent: Used in the modification of proteins, peptides, and antibodies due to the electrophilic nature of the vinyl sulfone group reacting with nucleophilic thiols.
• Polymer Chemistry: Acts as a cross-linking agent or monomer in the synthesis of specialty polymers and functional materials.
• Agrochemical Research: Employed in the synthesis of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probes: Utilized in the design of activity-based probes for studying enzyme function and mechanism.
• Dye and Pigment Synthesis: Functions as an intermediate in the production of advanced colorants and photographic chemicals.

Basic Information

Product Name	p-Nitrophenylvinyl Sulfone
CAS No.	5535-55-7
Molecular Formula	C8H7NO4S
Molecular Weight	213.21 g/mol
Synonyms	1-(Ethenesulfonyl)-4-nitrobenzene; 4-Nitrophenyl Vinyl Sulfone; (4-Nitrophenyl)ethenesulfonate; p-Nitrophenyl Vinylsulfone; Vinyl 4-Nitrophenyl Sulfone; 4-NPS; NSC 401122
EINECS	226-879-5

Quality Control

Our p-Nitrophenylvinyl Sulfone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	142 - 147 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.