Description

2-Chloro-1-Ethoxy-4-Nitrobenzene is a versatile halogenated nitroaromatic ether compound, serving as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both electron-withdrawing and alkoxy substituents, makes it a valuable precursor for constructing complex molecules. This compound is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a substituted nitrobenzene scaffold.
• Agrochemical Synthesis: Used in the production of herbicides, pesticides, and fungicides, where its chloronitrobenzene core is functionalized into target molecules.
• Dye and Pigment Manufacturing: Serves as a precursor in the synthesis of azo dyes and other complex colorants.
• Organic Synthesis Research: Employed in academic and industrial R&D for cross-coupling reactions, nucleophilic aromatic substitution, and reduction reactions to yield aniline derivatives.
• Material Science: Potential monomer or modifying agent in the synthesis of specialty polymers and liquid crystals.

Basic Information

Product Name	2-Chloro-1-Ethoxy-4-Nitrobenzene
CAS No.	5493-71-0
Molecular Formula	C8H8ClNO3
Molecular Weight	201.61 g/mol
Synonyms	1-Chloro-2-ethoxy-4-nitrobenzene; 2-Chloro-4-nitroanisole; 4-Nitro-2-chloroanisole; 2-Chloro-4-nitro-1-ethoxybenzene; 2-Chloro-4-nitroanisole; 2-Chloro-4-nitrophenyl ethyl ether; 4-Nitro-2-chlorophenetole; 2-Chloro-1-ethoxy-4-nitrobenzene
EINECS	226-842-2

Quality Control

Our 2-Chloro-1-Ethoxy-4-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.